Cocaine metabolism, as described in the Journal of Analytical Toxicology, is how the body processes cocaine. Cocaine’s pharmacokinetic and pharmacodynamics features help explain how the substance influences the body systems and how soon it exits after consumption. Since cocaine is metabolized differently based on how it reaches the body, these mechanisms can change slightly depending on its use.
When cocaine is smoked or injected, drug levels in the circulation rise quickly, leading to a powerful high. When the substance is sniffed or taken through the mucosal surfaces, it requires a little longer to take action; these routes result in a less strong commencement of the high that lasts around an hour. In all circumstances, the time taken for a drug to reach its maximum levels in the body depends largely on the person’s peculiar biochemistry.
Cocaine is metabolized and broken into smaller components called metabolites once it enters the body. Despite the fact that inhaled cocaine takes longer to metabolize than injected or smoked cocaine, the primary metabolite of cocaine, benzoylecgonine, is present in the blood after 15-30 min irrespective of the type of administration.
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